Biology of Aging Portal

Genes
Name	Description
Abscess	An abscess (Latin: abscessus) is a collection of pus (dead neutrophils) that has accumulated in a cavity formed by the tissue on the basis of an infectious process (usually caused by bacteria or parasites) or other foreign materials (e.g. splinters, bullet wounds, or injecting needles). It is a defensive reaction of the tissue to prevent the spread of infectious materials to other parts of the body. Wikipedia
Foreign Bodies	In physiology, a foreign body (Latin: corpus alienum) is any object originating outside the body. In machinery, it can mean any unwanted intruding object. Wikipedia
Uterine Cervical Neoplasms	Tumors or cancer of the UTERINE CERVIX. MeSH Definition
Mouth Neoplasms	Oral cancer is any cancerous tissue growth located in the mouth. It may arise as a primary lesion originating in any of the oral tissues, by metastasis from a distant site of origin, or by extension from a neighboring anatomic structure, such as the nasal cavity or the maxillary sinus. Oral cancers may originate in any of the tissues of the mouth, and may be of varied histologic types: teratoma, adenocarcinoma derived from a major or minor salivary gland, lymphoma from tonsillar or other lymphoid tissue, or melanoma from the pigment producing cells of the oral mucosa. Far and away the most common oral cancer is squamous cell carcinoma, originating in the tissues that line the mouth and lips. Oral or mouth cancer most commonly involves the tissue of the lips or the tongue. It may also occur on the floor of the mouth, cheek lining, gingiva (gums), or palate (roof of the mouth). Most oral cancers look very similar under the microscope and are called squamous cell carcinoma. These are malignant and tend to spread rapidly. Wikipedia
DNA Virus Infections	Infection caused by a DNA virus, a virus that has DNA as its genetic material and replicates using a DNA-dependent DNA polymerase. Wikipedia
Inflammatory Bowel Diseases	In medicine, inflammatory bowel disease (IBD) is a group of inflammatory conditions of the large intestine and, in some cases, the small intestine. Wikipedia
Digestive System Neoplasms	Digestive system neoplasms are tumors which affect the digestive system. Wikipedia
Pancreatitis	Inflammation of the pancreas. Chronic pancreatitis may cause diabetes and problems with digestion. Pain is the primary symptom. GHR - Glossary
Blood Platelet Disorders	Platelets, or thrombocytes, are the cells circulating in the blood that are involved in the cellular mechanisms of primary hemostasis leading to the formation of blood clots. Dysfunction or low levels of platelets predisposes to bleeding, while high levels, although usually asymptomatic, may increase the risk of thrombosis. An abnormality or disease of the platelets is called a thrombocytopathy.[1] Wikipedia
Protozoan Infections	A condition which is characterized by an infection caused by protozoans. Protozoa are microorganisms that differ from bacteria in that they are larger and possess a nucleus surrounded by a membrane. Several species of protozoa can be transmitted through water and cause disease in humans, including Giardia, Cryptosporidium, Cyclospora, Entamoeba and Isospora. Wikipedia
Osteoporosis	Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (osteoporosis, postmenopausal) and age-related or senile osteoporosis. GHR - Glossary
Stomach Neoplasms	Stomach cancer can develop in any part of the stomach and may spread throughout the stomach and to other organs; particularly the esophagus and the small intestine. Stomach cancer causes nearly one million deaths worldwide per year.[1] Wikipedia
Lung Diseases, Interstitial	A heterogeneous group of noninfectious, nonmalignant disorders of the lower respiratory tract, affecting primarily the alveolar wall structures but also often involving the small airways and blood vessels of the lung parenchyma. "Interstitial" refers to the fact that the interstitium of the alveolar walls is thickened, usually by fibrosis. This group of diseases is usually inflammatory. (Dorland, 27th ed; Wyngarden, Cecil Textbook of Medicine, 19th ed, p396) MeSH Definition
Streptococcal Infections	Streptococcal infections (strep for short) cause a variety of health problems. There are two types: group A and group B. Antibiotics are used to treat both. MedlinePlus health topic
Sarcomastigophora Infections	The phylum Sarcomastigophora includes many unicellular or colonial, autotrophic, or heterotrophic organisms. The two main sub-phyla are Mastigophora and Sarcodina. Wikipedia
Autoimmune Diseases	Your body's immune system protects you from disease and infection. But if you have an autoimmune disease, your immune system attacks itself by mistake. Autoimmune diseases can affect many parts of the body. These diseases tend to run in families. Women - particularly African-American, Hispanic-American, and Native-American women - have a higher risk for some autoimmune diseases. MedlinePlus health topic
Sexually Transmitted Diseases, Bacterial	Bacterial diseases transmitted or propagated by sexual conduct. MeSH Definition
Adnexal Diseases	Diseases of the uterine appendages (ADNEXA UTERI) including diseases involving the OVARY, the FALLOPIAN TUBES, and ligaments of the uterus (BROAD LIGAMENT; ROUND LIGAMENT). MeSH Definition
Urologic Neoplasms	Tumors or cancer of the URINARY TRACT in either the male or the female. MeSH Definition
Adenoma	A benign epithelial tumor with a glandular organization. GHR - Glossary
Adenocarcinoma	Carcinoma derived from glandular tissue or in which tumor cells form recognizable glandular structures. GHR - Glossary
Musculoskeletal Abnormalities	Congenital structural abnormalities and deformities of the musculoskeletal system. MeSH Definition
Gram-Negative Bacterial Infections	Gram-negative bacteria are those bacteria that do not retain crystal violet dye in the Gram staining protocol.[1] Gram-positive bacteria will retain the crystal violet dye when washed in a decolorizing solution. In a Gram stain test, a counterstain (commonly safranin) is added after the crystal violet, coloring all Gram-negative bacteria a red or pink color. The test itself is useful in classifying two distinct types of bacteria based on structural differences in their cell walls. Wikipedia
Nervous System Malformations	Structural abnormalities of the central or peripheral nervous system resulting primarily from defects of embryogenesis. MeSH Definition
Shock	1. A sudden or violent disturbance in the mental or emotional faculties. 2. A state of profound depression of the vital processes of the body that is characterized by pallor, rapid but weak pulse, rapid and shallow respiration, reduced total blood volume, and low blood pressure and that is caused usually by severe especially crushing injuries, hemorrhage, burns, or major surgery. GHR - Glossary
Neoplastic Processes	Neoplasia (new growth in Greek) is the abnormal proliferation of cells, resulting in a neoplasm. [1] [2] Neoplasia is the scientific term for the group of diseases commonly called tumor or cancer. [3] Wikipedia
Burns	A burn is damage to your body's tissues caused by heat, chemicals, electricity, sunlight or radiation. Scalds from hot liquids and steam, building fires and flammable liquids and gases are the most common causes of burns. MedlinePlus health topic
Genital Neoplasms, Male	Tumor or cancer of the MALE GENITALIA. Wikipedia
Dermatitis	A rash is an area of irritated or swollen skin. It might be red and itchy, bumpy, scaly, crusty or blistered. Rashes are a symptom of many different medical conditions. Things that can cause a rash include other diseases, irritating substances, allergies and your genetic makeup. MedlinePlus health topic
Mycoses	Mycosis (plural: mycoses) is a condition in which fungi pass the resistance barriers of the human or animal body and establish infections. Wikipedia

Abscess

An abscess (Latin: abscessus) is a collection of pus (dead neutrophils) that has accumulated in a cavity formed by the tissue on the basis of an infectious process (usually caused by bacteria or parasites) or other foreign materials (e.g. splinters, bullet wounds, or injecting needles). It is a defensive reaction of the tissue to prevent the spread of infectious materials to other parts of the body. Wikipedia

Foreign Bodies

In physiology, a foreign body (Latin: corpus alienum) is any object originating outside the body. In machinery, it can mean any unwanted intruding object. Wikipedia

Uterine Cervical Neoplasms

Tumors or cancer of the UTERINE CERVIX. MeSH Definition

Mouth Neoplasms

Oral cancer is any cancerous tissue growth located in the mouth. It may arise as a primary lesion originating in any of the oral tissues, by metastasis from a distant site of origin, or by extension from a neighboring anatomic structure, such as the nasal cavity or the maxillary sinus. Oral cancers may originate in any of the tissues of the mouth, and may be of varied histologic types: teratoma, adenocarcinoma derived from a major or minor salivary gland, lymphoma from tonsillar or other lymphoid tissue, or melanoma from the pigment producing cells of the oral mucosa. Far and away the most common oral cancer is squamous cell carcinoma, originating in the tissues that line the mouth and lips. Oral or mouth cancer most commonly involves the tissue of the lips or the tongue. It may also occur on the floor of the mouth, cheek lining, gingiva (gums), or palate (roof of the mouth). Most oral cancers look very similar under the microscope and are called squamous cell carcinoma. These are malignant and tend to spread rapidly. Wikipedia

DNA Virus Infections

Infection caused by a DNA virus, a virus that has DNA as its genetic material and replicates using a DNA-dependent DNA polymerase. Wikipedia

Inflammatory Bowel Diseases

In medicine, inflammatory bowel disease (IBD) is a group of inflammatory conditions of the large intestine and, in some cases, the small intestine. Wikipedia

Digestive System Neoplasms

Digestive system neoplasms are tumors which affect the digestive system. Wikipedia

Pancreatitis

Inflammation of the pancreas. Chronic pancreatitis may cause diabetes and problems with digestion. Pain is the primary symptom. GHR - Glossary

Blood Platelet Disorders

Platelets, or thrombocytes, are the cells circulating in the blood that are involved in the cellular mechanisms of primary hemostasis leading to the formation of blood clots. Dysfunction or low levels of platelets predisposes to bleeding, while high levels, although usually asymptomatic, may increase the risk of thrombosis. An abnormality or disease of the platelets is called a thrombocytopathy.[1] Wikipedia

Protozoan Infections

A condition which is characterized by an infection caused by protozoans. Protozoa are microorganisms that differ from bacteria in that they are larger and possess a nucleus surrounded by a membrane. Several species of protozoa can be transmitted through water and cause disease in humans, including Giardia, Cryptosporidium, Cyclospora, Entamoeba and Isospora. Wikipedia

Osteoporosis

Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (osteoporosis, postmenopausal) and age-related or senile osteoporosis. GHR - Glossary

Stomach Neoplasms

Stomach cancer can develop in any part of the stomach and may spread throughout the stomach and to other organs; particularly the esophagus and the small intestine. Stomach cancer causes nearly one million deaths worldwide per year.[1] Wikipedia

Lung Diseases, Interstitial

A heterogeneous group of noninfectious, nonmalignant disorders of the lower respiratory tract, affecting primarily the alveolar wall structures but also often involving the small airways and blood vessels of the lung parenchyma. "Interstitial" refers to the fact that the interstitium of the alveolar walls is thickened, usually by fibrosis. This group of diseases is usually inflammatory. (Dorland, 27th ed; Wyngarden, Cecil Textbook of Medicine, 19th ed, p396) MeSH Definition

Streptococcal Infections

Streptococcal infections (strep for short) cause a variety of health problems. There are two types: group A and group B. Antibiotics are used to treat both. MedlinePlus health topic

Sarcomastigophora Infections

The phylum Sarcomastigophora includes many unicellular or colonial, autotrophic, or heterotrophic organisms. The two main sub-phyla are Mastigophora and Sarcodina. Wikipedia

Autoimmune Diseases

Your body's immune system protects you from disease and infection. But if you have an autoimmune disease, your immune system attacks itself by mistake. Autoimmune diseases can affect many parts of the body. These diseases tend to run in families. Women - particularly African-American, Hispanic-American, and Native-American women - have a higher risk for some autoimmune diseases. MedlinePlus health topic

Sexually Transmitted Diseases, Bacterial

Bacterial diseases transmitted or propagated by sexual conduct. MeSH Definition

Adnexal Diseases

Diseases of the uterine appendages (ADNEXA UTERI) including diseases involving the OVARY, the FALLOPIAN TUBES, and ligaments of the uterus (BROAD LIGAMENT; ROUND LIGAMENT). MeSH Definition

Urologic Neoplasms

Tumors or cancer of the URINARY TRACT in either the male or the female. MeSH Definition

Adenoma

A benign epithelial tumor with a glandular organization. GHR - Glossary

Adenocarcinoma

Carcinoma derived from glandular tissue or in which tumor cells form recognizable glandular structures. GHR - Glossary

Musculoskeletal Abnormalities

Congenital structural abnormalities and deformities of the musculoskeletal system. MeSH Definition

Gram-Negative Bacterial Infections

Gram-negative bacteria are those bacteria that do not retain crystal violet dye in the Gram staining protocol.[1] Gram-positive bacteria will retain the crystal violet dye when washed in a decolorizing solution. In a Gram stain test, a counterstain (commonly safranin) is added after the crystal violet, coloring all Gram-negative bacteria a red or pink color. The test itself is useful in classifying two distinct types of bacteria based on structural differences in their cell walls. Wikipedia

Nervous System Malformations

Structural abnormalities of the central or peripheral nervous system resulting primarily from defects of embryogenesis. MeSH Definition

Shock

1. A sudden or violent disturbance in the mental or emotional faculties. 2. A state of profound depression of the vital processes of the body that is characterized by pallor, rapid but weak pulse, rapid and shallow respiration, reduced total blood volume, and low blood pressure and that is caused usually by severe especially crushing injuries, hemorrhage, burns, or major surgery. GHR - Glossary

Neoplastic Processes

Neoplasia (new growth in Greek) is the abnormal proliferation of cells, resulting in a neoplasm. [1] [2] Neoplasia is the scientific term for the group of diseases commonly called tumor or cancer. [3] Wikipedia

Burns

A burn is damage to your body's tissues caused by heat, chemicals, electricity, sunlight or radiation. Scalds from hot liquids and steam, building fires and flammable liquids and gases are the most common causes of burns. MedlinePlus health topic

Genital Neoplasms, Male

Tumor or cancer of the MALE GENITALIA. Wikipedia

Dermatitis

A rash is an area of irritated or swollen skin. It might be red and itchy, bumpy, scaly, crusty or blistered. Rashes are a symptom of many different medical conditions. Things that can cause a rash include other diseases, irritating substances, allergies and your genetic makeup. MedlinePlus health topic

Mycoses

Mycosis (plural: mycoses) is a condition in which fungi pass the resistance barriers of the human or animal body and establish infections. Wikipedia

Aging genes and diseases for:

Browse the Tree of Life

Explore Biomedical Literature

Other Tools

Sponsors

Mus musculus

House Mouse