Biology of Aging Portal

Genes
Name	Description
Breast Neoplasms	Breast cancer is a cancer that starts in the cells of the breast. Worldwide, breast cancer is the second most common type of cancer after lung cancer (10.4% of all cancer incidence, both sexes counted) and the fifth most common cause of cancer death. Worldwide, breast cancer is by far the most common cancer amongst women, with an incidence rate more than twice that of colorectal cancer and cervical cancer and about three times that of lung cancer. However breast cancer mortality worldwide is just 25% greater than that of lung cancer in women. Wikipedia
Otorhinolaryngologic Neoplasms	Otolaryngology is the branch of medicine that specializes in the diagnosis and treatment of ear, nose, throat, and head & neck disorders. The full name of the specialty is otolaryngology-head and neck surgery. Practitioners are called otolaryngologists-head and neck surgeons, or sometimes otorhinolaryngologists (ORL). A commonly used term for this specialty is ENT (ear, nose and throat). The term comes from the Greek ωτολαρυγγολογία (oto = genitive for ear, laryngo = genitive for larynx/throat, logy = study) and it literally means the study of ear and neck. The full term ωτορρινολαρυγγολογία (otorhinolaryngology), also includes rhino, which is the genitive of nose. Wikipedia
Arthritis, Rheumatoid	A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. Wikipedia
Embolism	Blocking of a blood vessel by a blood clot or foreign matter that has been transported from a distant site by the blood stream. GHR - Glossary
Metabolism, Inborn Errors	Errors in metabolic processes resulting from inborn genetic mutations that are inherited or acquired in utero. Wikipedia
Neoplasms by Histologic Type	A collective term for the various histological types of neoplasms. MeSH Definition
Calculi	Calculus is Latin for pebble, and has a number of meanings in English: Wikipedia
Neoplasms, Vascular Tissue	Neoplasms composed of vascular tissue. This concept does not refer to neoplasms located in blood vessels. MeSH Definition
Poisoning	A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it or absorb it through your skin. MedlinePlus health topic
Gastrointestinal Neoplasms	Tumors or cancer of the gastrointestinal tract. MeSH Definition
Endocrine Gland Neoplasms	An endocrine gland neoplasm is a neoplasm affecting one or more glands of the endocrine system. Wikipedia
Obstetric Labor Complications	Medical problems associated with OBSTETRIC LABOR, such as BREECH PRESENTATION; PREMATURE OBSTETRIC LABOR; HEMORRHAGE; or others. These complications can affect the well-being of the mother, the FETUS, or both. MeSH Definition
Pancreatic Diseases	The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Problems with the pancreas can lead to many health problems. These include MedlinePlus health topic
Pharyngeal Diseases	The pharynx (plural: pharynges) is the part of the neck and throat situated immediately posterior to (behind) the mouth and nasal cavity, and cranial, or superior, to the esophagus, larynx, and trachea. Wikipedia
Gastrointestinal Hemorrhage	Gastrointestinal bleeding or gastrointestinal hemorrhage describes every form of hemorrhage (loss of blood) in the gastrointestinal tract, from the pharynx to the rectum. It has diverse causes, and a medical history, as well as physical examination, generally distinguishes between the main forms. The degree of bleeding can range from nearly undetectable to acute, massive, life-threatening bleeding. Wikipedia
Bile Duct Diseases	Diseases in any part of the ductal system of the BILIARY TRACT from the smallest BILE CANALICULI to the largest COMMON BILE DUCT. MeSH Definition
Cross Infection	Any infection which a patient contracts in a health-care institution. MeSH Definition
Spinal Cord Diseases	Your spinal cord is the part of your nervous system that relays messages to and from your brain. It is housed inside your vertebrae, which are the bone disks that make up your spine. Normally, your vertebrae protect your spinal cord. If they don't, you can sustain a spinal cord injury. Besides injuries, the spinal cord can develop MedlinePlus health topic
Pleural Diseases	In human anatomy, the pleural cavity is a body cavity containing the lungs; the lungs are surrounded by two serous membranes, the pleurae. The outer pleura (parietal pleura) covers and is attached to the chest wall. The inner pleura (visceral pleura) covers and is attached to the lung and other structures, i.e. blood vessels, bronchi and nerves. Between the two is a thin space known as the pleural space, which normally contains a small amount of pleural fluid. Wikipedia
Lymphatic Metastasis	Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. MeSH Definition
Skull Neoplasms	Neoplasms of the bony part of the skull. MeSH Definition
Fetal Diseases	Pathophysiological conditions of the FETUS in the UTERUS. Some fetal diseases may be treated with FETAL THERAPIES. MeSH Definition
Uterine Cervical Diseases	The cervix (from Latin neck) is the lower, narrow portion of the uterus where it joins with the top end of the vagina. It is cylindrical or conical in shape and protrudes through the upper anterior vaginal wall. Approximately half its length is visible with appropriate medical equipment; the remainder lies above the vagina beyond view. It is occasionally called cervix uteri, or neck of the uterus. Wikipedia
Hemorrhagic Disorders	Spontaneous or near spontaneous bleeding caused by a defect in clotting mechanisms (BLOOD COAGULATION DISORDERS) or another abnormality causing a structural flaw in the blood vessels (HEMOSTATIC DISORDERS). MeSH Definition
Gonadal Disorders	Pathological processes of the OVARIES or the TESTES. MeSH Definition
Hypersensitivity	Hypersensitivity refers to undesirable (damaging, discomfort-producing and sometimes fatal) reactions produced by the normal immune system. Hypersensitivity reactions require a pre-sensitized (immune) state of the host. The four-group classification was expounded by P. H. G. Gell and Robin Coombs in 1963. Wikipedia
Brain Neoplasms	A brain tumor is any intracranial tumor created by abnormal and uncontrolled cell division, normally either in the brain itself (neurons, glial cells (astrocytes, oligodendrocytes, ependymal cells), lymphatic tissue, blood vessels), in the cranial nerves (myelin-producing Schwann cells), in the brain envelopes (meninges), skull, pituitary and pineal gland, or spread from cancers primarily located in other organs (metastatic tumors). Primary (true) brain tumors are commonly located in the posterior cranial fossa in children and in the anterior two-thirds of the cerebral hemispheres in adults, although they can affect any part of the brain. In the United States in the year 2005, it was estimated that there were 43,800 new cases of brain tumors (Central Brain Tumor Registry of the United States, Primary Brain Tumors in the United States, Statistical Report, 2005 - 2006),[1] which accounted for 1.4 percent of all cancers, 2.4 percent of all cancer deaths,[2] and 20–25 percent of pediatric cancers.[2][3] Ultimately, it is estimated that there are 13,000 deaths/year as a result of brain tumors.[1] Wikipedia
Bone Diseases, Metabolic	MeSH Definition
Anemia, Hemolytic	A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES). Wikipedia
Urinary Bladder Diseases	Pathological processes of the URINARY BLADDER. MeSH Definition

Breast Neoplasms

Breast cancer is a cancer that starts in the cells of the breast. Worldwide, breast cancer is the second most common type of cancer after lung cancer (10.4% of all cancer incidence, both sexes counted) and the fifth most common cause of cancer death. Worldwide, breast cancer is by far the most common cancer amongst women, with an incidence rate more than twice that of colorectal cancer and cervical cancer and about three times that of lung cancer. However breast cancer mortality worldwide is just 25% greater than that of lung cancer in women. Wikipedia

Otorhinolaryngologic Neoplasms

Otolaryngology is the branch of medicine that specializes in the diagnosis and treatment of ear, nose, throat, and head & neck disorders. The full name of the specialty is otolaryngology-head and neck surgery. Practitioners are called otolaryngologists-head and neck surgeons, or sometimes otorhinolaryngologists (ORL). A commonly used term for this specialty is ENT (ear, nose and throat). The term comes from the Greek ωτολαρυγγολογία (oto = genitive for ear, laryngo = genitive for larynx/throat, logy = study) and it literally means the study of ear and neck. The full term ωτορρινολαρυγγολογία (otorhinolaryngology), also includes rhino, which is the genitive of nose. Wikipedia

Arthritis, Rheumatoid

A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. Wikipedia

Embolism

Blocking of a blood vessel by a blood clot or foreign matter that has been transported from a distant site by the blood stream. GHR - Glossary

Metabolism, Inborn Errors

Errors in metabolic processes resulting from inborn genetic mutations that are inherited or acquired in utero. Wikipedia

Neoplasms by Histologic Type

A collective term for the various histological types of neoplasms. MeSH Definition

Calculi

Calculus is Latin for pebble, and has a number of meanings in English: Wikipedia

Neoplasms, Vascular Tissue

Neoplasms composed of vascular tissue. This concept does not refer to neoplasms located in blood vessels. MeSH Definition

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it or absorb it through your skin. MedlinePlus health topic

Gastrointestinal Neoplasms

Tumors or cancer of the gastrointestinal tract. MeSH Definition

Endocrine Gland Neoplasms

An endocrine gland neoplasm is a neoplasm affecting one or more glands of the endocrine system. Wikipedia

Obstetric Labor Complications

Medical problems associated with OBSTETRIC LABOR, such as BREECH PRESENTATION; PREMATURE OBSTETRIC LABOR; HEMORRHAGE; or others. These complications can affect the well-being of the mother, the FETUS, or both. MeSH Definition

Pancreatic Diseases

The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Problems with the pancreas can lead to many health problems. These include MedlinePlus health topic

Pharyngeal Diseases

The pharynx (plural: pharynges) is the part of the neck and throat situated immediately posterior to (behind) the mouth and nasal cavity, and cranial, or superior, to the esophagus, larynx, and trachea. Wikipedia

Gastrointestinal Hemorrhage

Gastrointestinal bleeding or gastrointestinal hemorrhage describes every form of hemorrhage (loss of blood) in the gastrointestinal tract, from the pharynx to the rectum. It has diverse causes, and a medical history, as well as physical examination, generally distinguishes between the main forms. The degree of bleeding can range from nearly undetectable to acute, massive, life-threatening bleeding. Wikipedia

Bile Duct Diseases

Diseases in any part of the ductal system of the BILIARY TRACT from the smallest BILE CANALICULI to the largest COMMON BILE DUCT. MeSH Definition

Cross Infection

Any infection which a patient contracts in a health-care institution. MeSH Definition

Spinal Cord Diseases

Your spinal cord is the part of your nervous system that relays messages to and from your brain. It is housed inside your vertebrae, which are the bone disks that make up your spine. Normally, your vertebrae protect your spinal cord. If they don't, you can sustain a spinal cord injury. Besides injuries, the spinal cord can develop MedlinePlus health topic

Pleural Diseases

In human anatomy, the pleural cavity is a body cavity containing the lungs; the lungs are surrounded by two serous membranes, the pleurae. The outer pleura (parietal pleura) covers and is attached to the chest wall. The inner pleura (visceral pleura) covers and is attached to the lung and other structures, i.e. blood vessels, bronchi and nerves. Between the two is a thin space known as the pleural space, which normally contains a small amount of pleural fluid. Wikipedia

Lymphatic Metastasis

Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. MeSH Definition

Skull Neoplasms

Neoplasms of the bony part of the skull. MeSH Definition

Fetal Diseases

Pathophysiological conditions of the FETUS in the UTERUS. Some fetal diseases may be treated with FETAL THERAPIES. MeSH Definition

Uterine Cervical Diseases

The cervix (from Latin neck) is the lower, narrow portion of the uterus where it joins with the top end of the vagina. It is cylindrical or conical in shape and protrudes through the upper anterior vaginal wall. Approximately half its length is visible with appropriate medical equipment; the remainder lies above the vagina beyond view. It is occasionally called cervix uteri, or neck of the uterus. Wikipedia

Hemorrhagic Disorders

Spontaneous or near spontaneous bleeding caused by a defect in clotting mechanisms (BLOOD COAGULATION DISORDERS) or another abnormality causing a structural flaw in the blood vessels (HEMOSTATIC DISORDERS). MeSH Definition

Gonadal Disorders

Pathological processes of the OVARIES or the TESTES. MeSH Definition

Hypersensitivity

Hypersensitivity refers to undesirable (damaging, discomfort-producing and sometimes fatal) reactions produced by the normal immune system. Hypersensitivity reactions require a pre-sensitized (immune) state of the host. The four-group classification was expounded by P. H. G. Gell and Robin Coombs in 1963. Wikipedia

Brain Neoplasms

A brain tumor is any intracranial tumor created by abnormal and uncontrolled cell division, normally either in the brain itself (neurons, glial cells (astrocytes, oligodendrocytes, ependymal cells), lymphatic tissue, blood vessels), in the cranial nerves (myelin-producing Schwann cells), in the brain envelopes (meninges), skull, pituitary and pineal gland, or spread from cancers primarily located in other organs (metastatic tumors). Primary (true) brain tumors are commonly located in the posterior cranial fossa in children and in the anterior two-thirds of the cerebral hemispheres in adults, although they can affect any part of the brain. In the United States in the year 2005, it was estimated that there were 43,800 new cases of brain tumors (Central Brain Tumor Registry of the United States, Primary Brain Tumors in the United States, Statistical Report, 2005 - 2006),[1] which accounted for 1.4 percent of all cancers, 2.4 percent of all cancer deaths,[2] and 20–25 percent of pediatric cancers.[2][3] Ultimately, it is estimated that there are 13,000 deaths/year as a result of brain tumors.[1] Wikipedia

Bone Diseases, Metabolic

MeSH Definition

Anemia, Hemolytic

A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES). Wikipedia

Urinary Bladder Diseases

Pathological processes of the URINARY BLADDER. MeSH Definition

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