Biology of Aging Portal

Genes
Name	Description
Intestinal Diseases	Diseases of the intestine. In anatomy, the intestine is the segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine. In humans, the small intestine is further subdivided into the duodenum, jejunum and ileum while the large intestine is subdivided into the cecum and colon. Wikipedia
HIV Infections	Human immunodeficiency virus (HIV) is a retrovirus that can lead to acquired immunodeficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. Previous names for the virus include human T-lymphotropic virus-III (HTLV-III), lymphadenopathy-associated virus (LAV), and AIDS-associated retrovirus (ARV). Wikipedia
Sexually Transmitted Diseases, Viral	Viral diseases which are transmitted or propagated by sexual conduct. Wikipedia
Mouth Diseases	Diseases of the mouth (or oral cavity). Wikipedia
Embolism and Thrombosis	A collective term for pathological conditions which are caused by the formation of a blood clot or thrombus in a blood vessel, or by blocking of a blood vessel with an embolus, undissolved materials in the blood stream. MeSH Definition
Arrhythmias, Cardiac	Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction. MeSH Definition
Retroviridae Infections	Infection by a retrovirus. Wikipedia
Genetic Diseases, Inborn	Diseases that are caused by genetic mutations present during embryo or fetal development, although they may be observed later in life. The mutations may be inherited from a parent's genome or they may be acquired in utero. MeSH Definition
Chronic Disease	In medicine, a chronic disease is a disease that is long-lasting or recurrent. The term chronic describes the course of the disease, or its rate of onset and development. A chronic course is distinguished from a recurrent course; recurrent diseases relapse repeatedly, with periods of remission in between. As an adjective, chronic can refer to a persistent and lasting medical condition. Chronicity is usually applied to a condition that lasts more than three months. Wikipedia
Respiratory Tract Infections	Respiratory tract infections can refer to lower respiratory tract infections -- Often used as a synonym for pneumonia, but can also be applied to other types of infection including lung abscess, acute bronchitis, and emphysema. Symptoms include shortness of breath, weakness, high fever, coughing and fatigue -- and upper respiratory tract infections -- such as rhinosinusitis (common cold), sinusitis, pharyngitis/tonsillitis, laryngitis and sometimes bronchitis. Symptoms commonly include nasal congestion, cough, running nose, sore throat, fever, facial pressure and sneezing. Wikipedia
Joint Diseases	A joint is the location at which two or more bones make contact.[1] They are constructed to allow movement and provide mechanical support, and are classified structurally and functionally.[2] Wikipedia
Head and Neck Neoplasms	The term head and neck cancer refers to a group of biologically similar cancers originating from the upper aerodigestive tract, including the lip, oral cavity (mouth), nasal cavity, paranasal sinuses, pharynx, and larynx. Most head and neck cancers are squamous cell carcinomas, originating from the mucosal lining (epithelium) of these regions. Head and neck cancers often spread to the lymph nodes of the neck, and this is often the first (and sometimes only) manifestation of the disease at the time of diagnosis. Head and neck cancer is strongly associated with certain environmental and lifestyle risk factors, including tobacco smoking, alcohol consumption, and certain strains of the sexually transmitted human papillomavirus. Head and neck cancer is highly curable if detected early, usually with some form of surgery although chemotherapy and radiation therapy may also play an important role. Wikipedia
Tooth Diseases	Teeth (singular, tooth) are small white structures found in the jaws (or mouths) of many vertebrates that are used to tear, scrape, milk and chew food. Some animals, particularly carnivores, also use teeth for hunting or defense. The roots of teeth are covered by gums. Wikipedia
Bacterial Infections	Bacteria are living things that have only one cell. Under a microscope, they look like balls, rods or spirals. Most bacteria won't hurt you - less than 1 percent makes people sick. Many are helpful. But infectious bacteria can make you ill. They reproduce quickly in your body. Many give off chemicals called toxins, which can damage tissue and make you sick. Examples of bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. MedlinePlus health topic
Fractures, Bone	Breaks in bones. Wikipedia
Recurrence	The return of a sign, symptom, or disease after a remission. Wikipedia
Leukemia	Cancer of blood-forming tissue. GHR - Glossary
Substance-Related Disorders	Substance abuse is the overindulgence in and dependence of a drug or other chemical leading to effects that are detrimental to the individual's physical and mental health, or the welfare of others. Wikipedia
Hematologic Diseases	Diseases of the blood and related organs. Hematology is the branch of medicine that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases. Wikipedia
Myocardial Infarction	An acute episode of heart disease marked by the death or damage of heart muscle due to insufficient blood supply to the heart muscle usually as a result of a coronary thrombosis or a coronary occlusion and that is characterized especially by chest pain--called also myocardial infarction. GHR - Glossary
Cardiovascular Abnormalities	Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS. MeSH Definition
Respiration Disorders	Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available. MeSH Definition
Immunologic Deficiency Syndromes	In medicine, immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent. Most cases of immunodeficiency are acquired (secondary) but some people are born with defects in the immune system, or primary immunodeficiency. Transplant patients take medications to suppress their immune system as an anti-rejection measure. A person who has an immunodeficiency of any kind is said to be immunocompromised. An immunocompromised person may be particularly vulnerable to opportunistic infections, in addition to normal infections that could affect everyone. Wikipedia
Thrombosis	Formation and development of a thrombus or blood clot in the blood vessel. GHR - Glossary
Infant, Newborn, Diseases	Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts. MeSH Definition
Lung Diseases, Obstructive	Any disorder marked by persistent obstruction of bronchial air flow. MeSH Definition
Rheumatic Diseases	Rheumatism, rheumatic diseases, and rheumatic disorder are non-specific terms for medical problems affecting the heart, bones, joints, kidney, skin and lung. Wikipedia
Acute Disease	Disease having a short and relatively severe course. MeSH Definition
Genital Diseases, Male	Pathological processes involving the male reproductive tract. MeSH Definition
Gram-Positive Bacterial Infections	Gram-positive bacteria are those that are stained dark blue or violet by Gram staining. This is in contrast to Gram-negative bacteria, which cannot retain the crystal violet stain, instead taking up the counterstain (safranin) and appearing red or pink. Gram-positive organisms are able to retain the crystal violet stain because of the high amount of peptidoglycan in the cell wall. Gram-positive cell walls typically lack the outer membrane found in Gram-negative bacteria. Wikipedia

Intestinal Diseases

Diseases of the intestine. In anatomy, the intestine is the segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine. In humans, the small intestine is further subdivided into the duodenum, jejunum and ileum while the large intestine is subdivided into the cecum and colon. Wikipedia

HIV Infections

Human immunodeficiency virus (HIV) is a retrovirus that can lead to acquired immunodeficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. Previous names for the virus include human T-lymphotropic virus-III (HTLV-III), lymphadenopathy-associated virus (LAV), and AIDS-associated retrovirus (ARV). Wikipedia

Sexually Transmitted Diseases, Viral

Viral diseases which are transmitted or propagated by sexual conduct. Wikipedia

Mouth Diseases

Diseases of the mouth (or oral cavity). Wikipedia

Embolism and Thrombosis

A collective term for pathological conditions which are caused by the formation of a blood clot or thrombus in a blood vessel, or by blocking of a blood vessel with an embolus, undissolved materials in the blood stream. MeSH Definition

Arrhythmias, Cardiac

Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction. MeSH Definition

Retroviridae Infections

Infection by a retrovirus. Wikipedia

Genetic Diseases, Inborn

Diseases that are caused by genetic mutations present during embryo or fetal development, although they may be observed later in life. The mutations may be inherited from a parent's genome or they may be acquired in utero. MeSH Definition

Chronic Disease

In medicine, a chronic disease is a disease that is long-lasting or recurrent. The term chronic describes the course of the disease, or its rate of onset and development. A chronic course is distinguished from a recurrent course; recurrent diseases relapse repeatedly, with periods of remission in between. As an adjective, chronic can refer to a persistent and lasting medical condition. Chronicity is usually applied to a condition that lasts more than three months. Wikipedia

Respiratory Tract Infections

Respiratory tract infections can refer to lower respiratory tract infections -- Often used as a synonym for pneumonia, but can also be applied to other types of infection including lung abscess, acute bronchitis, and emphysema. Symptoms include shortness of breath, weakness, high fever, coughing and fatigue -- and upper respiratory tract infections -- such as rhinosinusitis (common cold), sinusitis, pharyngitis/tonsillitis, laryngitis and sometimes bronchitis. Symptoms commonly include nasal congestion, cough, running nose, sore throat, fever, facial pressure and sneezing. Wikipedia

Joint Diseases

A joint is the location at which two or more bones make contact.[1] They are constructed to allow movement and provide mechanical support, and are classified structurally and functionally.[2] Wikipedia

Head and Neck Neoplasms

The term head and neck cancer refers to a group of biologically similar cancers originating from the upper aerodigestive tract, including the lip, oral cavity (mouth), nasal cavity, paranasal sinuses, pharynx, and larynx. Most head and neck cancers are squamous cell carcinomas, originating from the mucosal lining (epithelium) of these regions. Head and neck cancers often spread to the lymph nodes of the neck, and this is often the first (and sometimes only) manifestation of the disease at the time of diagnosis. Head and neck cancer is strongly associated with certain environmental and lifestyle risk factors, including tobacco smoking, alcohol consumption, and certain strains of the sexually transmitted human papillomavirus. Head and neck cancer is highly curable if detected early, usually with some form of surgery although chemotherapy and radiation therapy may also play an important role. Wikipedia

Tooth Diseases

Teeth (singular, tooth) are small white structures found in the jaws (or mouths) of many vertebrates that are used to tear, scrape, milk and chew food. Some animals, particularly carnivores, also use teeth for hunting or defense. The roots of teeth are covered by gums. Wikipedia

Bacterial Infections

Bacteria are living things that have only one cell. Under a microscope, they look like balls, rods or spirals. Most bacteria won't hurt you - less than 1 percent makes people sick. Many are helpful. But infectious bacteria can make you ill. They reproduce quickly in your body. Many give off chemicals called toxins, which can damage tissue and make you sick. Examples of bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. MedlinePlus health topic

Fractures, Bone

Breaks in bones. Wikipedia

Recurrence

The return of a sign, symptom, or disease after a remission. Wikipedia

Leukemia

Cancer of blood-forming tissue. GHR - Glossary

Substance-Related Disorders

Substance abuse is the overindulgence in and dependence of a drug or other chemical leading to effects that are detrimental to the individual's physical and mental health, or the welfare of others. Wikipedia

Hematologic Diseases

Diseases of the blood and related organs. Hematology is the branch of medicine that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases. Wikipedia

Myocardial Infarction

An acute episode of heart disease marked by the death or damage of heart muscle due to insufficient blood supply to the heart muscle usually as a result of a coronary thrombosis or a coronary occlusion and that is characterized especially by chest pain--called also myocardial infarction. GHR - Glossary

Cardiovascular Abnormalities

Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS. MeSH Definition

Respiration Disorders

Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available. MeSH Definition

Immunologic Deficiency Syndromes

In medicine, immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent. Most cases of immunodeficiency are acquired (secondary) but some people are born with defects in the immune system, or primary immunodeficiency. Transplant patients take medications to suppress their immune system as an anti-rejection measure. A person who has an immunodeficiency of any kind is said to be immunocompromised. An immunocompromised person may be particularly vulnerable to opportunistic infections, in addition to normal infections that could affect everyone. Wikipedia

Thrombosis

Formation and development of a thrombus or blood clot in the blood vessel. GHR - Glossary

Infant, Newborn, Diseases

Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts. MeSH Definition

Lung Diseases, Obstructive

Any disorder marked by persistent obstruction of bronchial air flow. MeSH Definition

Rheumatic Diseases

Rheumatism, rheumatic diseases, and rheumatic disorder are non-specific terms for medical problems affecting the heart, bones, joints, kidney, skin and lung. Wikipedia

Acute Disease

Disease having a short and relatively severe course. MeSH Definition

Genital Diseases, Male

Pathological processes involving the male reproductive tract. MeSH Definition

Gram-Positive Bacterial Infections

Gram-positive bacteria are those that are stained dark blue or violet by Gram staining. This is in contrast to Gram-negative bacteria, which cannot retain the crystal violet stain, instead taking up the counterstain (safranin) and appearing red or pink. Gram-positive organisms are able to retain the crystal violet stain because of the high amount of peptidoglycan in the cell wall. Gram-positive cell walls typically lack the outer membrane found in Gram-negative bacteria. Wikipedia

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