Biology of Aging Portal

Genes
Name	Description
Infant, Newborn, Diseases	Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts. MeSH Definition
Recurrence	The return of a sign, symptom, or disease after a remission. Wikipedia
Myocardial Infarction	An acute episode of heart disease marked by the death or damage of heart muscle due to insufficient blood supply to the heart muscle usually as a result of a coronary thrombosis or a coronary occlusion and that is characterized especially by chest pain--called also myocardial infarction. GHR - Glossary
Tooth Diseases	Teeth (singular, tooth) are small white structures found in the jaws (or mouths) of many vertebrates that are used to tear, scrape, milk and chew food. Some animals, particularly carnivores, also use teeth for hunting or defense. The roots of teeth are covered by gums. Wikipedia
Neoplasm Metastasis	The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. MeSH Definition
Poisoning	A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it or absorb it through your skin. MedlinePlus health topic
Cardiovascular Abnormalities	Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS. MeSH Definition
Lung Neoplasms	Lung neoplasm or lung cancer is a disease of uncontrolled cell growth in tissues of the lung. This growth may lead to metastasis, invasion of adjacent tissue and infiltration beyond the lungs. The vast majority of primary lung cancers are carcinomas of the lung, derived from epithelial cells. Lung cancer, the most common cause of cancer-related death in men and the second most common in women, is responsible for 1.3 million deaths worldwide annually. In the UK, it is the most common site of fatal cancer in both men and women. The most common symptoms are shortness of breath, coughing (including coughing up blood), and weight loss. Wikipedia
Respiration Disorders	Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available. MeSH Definition
Thrombosis	Formation and development of a thrombus or blood clot in the blood vessel. GHR - Glossary
Gonadal Disorders	Pathological processes of the OVARIES or the TESTES. MeSH Definition
Neuroendocrine Tumors	Neuroendocrine tumors, or more properly gastro-entero-pancreatic or gastroenteropancreatic neuroendocrine tumors (GEP-NETs), are cancers of the interface between the endocrine (hormonal) system and the nervous system. Wikipedia
Lymphoma	Lymphoma is a cancer of a part of the immune system called the lymphatic system. There are many types of lymphoma. One type is called Hodgkin's disease. The rest are called non-Hodgkin's lymphoma. MedlinePlus health topic
Central Nervous System Neoplasms	A brain tumor is any intracranial tumor created by abnormal and uncontrolled cell division, normally either in the brain itself (neurons, glial cells (astrocytes, oligodendrocytes, ependymal cells), lymphatic tissue, blood vessels), in the cranial nerves (myelin-producing Schwann cells), in the brain envelopes (meninges), skull, pituitary and pineal gland, or spread from cancers primarily located in other organs (metastatic tumors). Primary (true) brain tumors are commonly located in the posterior cranial fossa in children and in the anterior two-thirds of the cerebral hemispheres in adults, although they can affect any part of the brain. In the United States in the year 2005, it was estimated that there were 43,800 new cases of brain tumors (Central Brain Tumor Registry of the United States, Primary Brain Tumors in the United States, Statistical Report, 2005 - 2006),[1] which accounted for 1.4 percent of all cancers, 2.4 percent of all cancer deaths,[2] and 20–25 percent of pediatric cancers.[2][3] Ultimately, it is estimated that there are 13,000 deaths/year as a result of brain tumors.[1] Wikipedia
Uterine Diseases	The uterus, or womb, is an important female reproductive organ. It is the place where a baby grows when a woman is pregnant. If you have a uterine disease, the first sign may be bleeding between periods or after sex. Causes of abnormal bleeding include hormones, thyroid problems, fibroids, polyps, cancer, infection or pregnancy. MedlinePlus health topic
Anemia	If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body. MedlinePlus health topic
Neoplasms, Experimental	Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms. MeSH Definition
Intestinal Neoplasms	Intestinal neoplasms can refer to: Wikipedia
Hepatitis	Your liver helps your body digest food, store energy and remove poisons. Hepatitis is a swelling of the liver that makes it stop working well. It can lead to scarring, called cirrhosis, or to cancer. MedlinePlus health topic
Respiratory Hypersensitivity	A form of hypersensitivity affecting the respiratory tract. It includes ASTHMA and RHINITIS, ALLERGIC, SEASONAL. MeSH Definition
Central Nervous System Infections	The central nervous system (CNS) of the vertebrate nervous system which is enclosed in meninges. It contains the majority of the nervous system, and consists of the brain (in vertebrates which have brains), and the spinal cord. Together with the peripheral nervous system, it has a fundamental role in the control of behavior. The CNS is contained within the dorsal cavity, with the brain within the cranial cavity, and the spinal cord in the spinal cavity. The brain is also protected by the skull, and the spinal cord is, in vertebrates, also protected by the vertebrae. [1] Wikipedia
Pancreatic Diseases	The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Problems with the pancreas can lead to many health problems. These include MedlinePlus health topic
Colonic Diseases	Your colon, also known as the large intestine, is part of your digestive system. It's a long, hollow tube at the end of your digestive tract where your body makes and stores stool. Many disorders affect the colon's ability to work properly. MedlinePlus health topic
Signs and Symptoms, Digestive	Digestive system manifestations of diseases of the gastrointestinal system or of other organs. MeSH Definition
Protozoan Infections	A condition which is characterized by an infection caused by protozoans. Protozoa are microorganisms that differ from bacteria in that they are larger and possess a nucleus surrounded by a membrane. Several species of protozoa can be transmitted through water and cause disease in humans, including Giardia, Cryptosporidium, Cyclospora, Entamoeba and Isospora. Wikipedia
Craniocerebral Trauma	Brain-computer interfaces • Traumatic Brain InjuryBrain regions • Clinical neuropsychologyCognitive neuroscience • Human brainNeuroanatomy • NeurophysiologyPhrenology • Common misconceptions Wikipedia
Neoplasms, Squamous Cell	Neoplasms composed of squamous cells of the epithelium. The concept does not refer to neoplasms located in tissue composed of squamous elements. Wikipedia
Muscular Diseases	Muscle (from Latin musculus, diminutive of mus mouse[1]) is contractile tissue of the body and is derived from the mesodermal layer of embryonic germ cells. Muscle cells contain contractile filaments that move past each other and change the size of the cell. They are classified as skeletal, cardiac, or smooth muscles. Their function is to produce force and cause motion. Muscles can cause either locomotion of the organism itself or movement of internal organs. Cardiac and smooth muscle contraction occurs without conscious thought and is necessary for survival. Examples are the contraction of the heart and peristalsis which pushes food through the digestive system. Voluntary contraction of the skeletal muscles is used to move the body and can be finely controlled. Examples are movements of the eye, or gross movements like the quadriceps muscle of the thigh. There are two broad types of voluntary muscle fibers: slow twitch and fast twitch. Slow twitch fibers contract for long periods of time but with little force while fast twitch fibers contract quickly and powerfully but fatigue very rapidly. Wikipedia
Renal Insufficiency	Renal failure or kidney failure is a situation in which the kidneys fail to function adequately. It is divided in acute and chronic forms; either form may be due to a large number of other medical problems. Wikipedia
Brain Neoplasms	A brain tumor is any intracranial tumor created by abnormal and uncontrolled cell division, normally either in the brain itself (neurons, glial cells (astrocytes, oligodendrocytes, ependymal cells), lymphatic tissue, blood vessels), in the cranial nerves (myelin-producing Schwann cells), in the brain envelopes (meninges), skull, pituitary and pineal gland, or spread from cancers primarily located in other organs (metastatic tumors). Primary (true) brain tumors are commonly located in the posterior cranial fossa in children and in the anterior two-thirds of the cerebral hemispheres in adults, although they can affect any part of the brain. In the United States in the year 2005, it was estimated that there were 43,800 new cases of brain tumors (Central Brain Tumor Registry of the United States, Primary Brain Tumors in the United States, Statistical Report, 2005 - 2006),[1] which accounted for 1.4 percent of all cancers, 2.4 percent of all cancer deaths,[2] and 20–25 percent of pediatric cancers.[2][3] Ultimately, it is estimated that there are 13,000 deaths/year as a result of brain tumors.[1] Wikipedia

Infant, Newborn, Diseases

Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts. MeSH Definition

Recurrence

The return of a sign, symptom, or disease after a remission. Wikipedia

Myocardial Infarction

An acute episode of heart disease marked by the death or damage of heart muscle due to insufficient blood supply to the heart muscle usually as a result of a coronary thrombosis or a coronary occlusion and that is characterized especially by chest pain--called also myocardial infarction. GHR - Glossary

Tooth Diseases

Teeth (singular, tooth) are small white structures found in the jaws (or mouths) of many vertebrates that are used to tear, scrape, milk and chew food. Some animals, particularly carnivores, also use teeth for hunting or defense. The roots of teeth are covered by gums. Wikipedia

Neoplasm Metastasis

The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. MeSH Definition

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it or absorb it through your skin. MedlinePlus health topic

Cardiovascular Abnormalities

Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS. MeSH Definition

Lung Neoplasms

Lung neoplasm or lung cancer is a disease of uncontrolled cell growth in tissues of the lung. This growth may lead to metastasis, invasion of adjacent tissue and infiltration beyond the lungs. The vast majority of primary lung cancers are carcinomas of the lung, derived from epithelial cells. Lung cancer, the most common cause of cancer-related death in men and the second most common in women, is responsible for 1.3 million deaths worldwide annually. In the UK, it is the most common site of fatal cancer in both men and women. The most common symptoms are shortness of breath, coughing (including coughing up blood), and weight loss. Wikipedia

Respiration Disorders

Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available. MeSH Definition

Thrombosis

Formation and development of a thrombus or blood clot in the blood vessel. GHR - Glossary

Gonadal Disorders

Pathological processes of the OVARIES or the TESTES. MeSH Definition

Neuroendocrine Tumors

Neuroendocrine tumors, or more properly gastro-entero-pancreatic or gastroenteropancreatic neuroendocrine tumors (GEP-NETs), are cancers of the interface between the endocrine (hormonal) system and the nervous system. Wikipedia

Lymphoma

Lymphoma is a cancer of a part of the immune system called the lymphatic system. There are many types of lymphoma. One type is called Hodgkin's disease. The rest are called non-Hodgkin's lymphoma. MedlinePlus health topic

Central Nervous System Neoplasms

A brain tumor is any intracranial tumor created by abnormal and uncontrolled cell division, normally either in the brain itself (neurons, glial cells (astrocytes, oligodendrocytes, ependymal cells), lymphatic tissue, blood vessels), in the cranial nerves (myelin-producing Schwann cells), in the brain envelopes (meninges), skull, pituitary and pineal gland, or spread from cancers primarily located in other organs (metastatic tumors). Primary (true) brain tumors are commonly located in the posterior cranial fossa in children and in the anterior two-thirds of the cerebral hemispheres in adults, although they can affect any part of the brain. In the United States in the year 2005, it was estimated that there were 43,800 new cases of brain tumors (Central Brain Tumor Registry of the United States, Primary Brain Tumors in the United States, Statistical Report, 2005 - 2006),[1] which accounted for 1.4 percent of all cancers, 2.4 percent of all cancer deaths,[2] and 20–25 percent of pediatric cancers.[2][3] Ultimately, it is estimated that there are 13,000 deaths/year as a result of brain tumors.[1] Wikipedia

Uterine Diseases

The uterus, or womb, is an important female reproductive organ. It is the place where a baby grows when a woman is pregnant. If you have a uterine disease, the first sign may be bleeding between periods or after sex. Causes of abnormal bleeding include hormones, thyroid problems, fibroids, polyps, cancer, infection or pregnancy. MedlinePlus health topic

Anemia

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body. MedlinePlus health topic

Neoplasms, Experimental

Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms. MeSH Definition

Intestinal Neoplasms

Intestinal neoplasms can refer to: Wikipedia

Hepatitis

Your liver helps your body digest food, store energy and remove poisons. Hepatitis is a swelling of the liver that makes it stop working well. It can lead to scarring, called cirrhosis, or to cancer. MedlinePlus health topic

Respiratory Hypersensitivity

A form of hypersensitivity affecting the respiratory tract. It includes ASTHMA and RHINITIS, ALLERGIC, SEASONAL. MeSH Definition

Central Nervous System Infections

The central nervous system (CNS) of the vertebrate nervous system which is enclosed in meninges. It contains the majority of the nervous system, and consists of the brain (in vertebrates which have brains), and the spinal cord. Together with the peripheral nervous system, it has a fundamental role in the control of behavior. The CNS is contained within the dorsal cavity, with the brain within the cranial cavity, and the spinal cord in the spinal cavity. The brain is also protected by the skull, and the spinal cord is, in vertebrates, also protected by the vertebrae. [1] Wikipedia

Pancreatic Diseases

The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Problems with the pancreas can lead to many health problems. These include MedlinePlus health topic

Colonic Diseases

Your colon, also known as the large intestine, is part of your digestive system. It's a long, hollow tube at the end of your digestive tract where your body makes and stores stool. Many disorders affect the colon's ability to work properly. MedlinePlus health topic

Signs and Symptoms, Digestive

Digestive system manifestations of diseases of the gastrointestinal system or of other organs. MeSH Definition

Protozoan Infections

A condition which is characterized by an infection caused by protozoans. Protozoa are microorganisms that differ from bacteria in that they are larger and possess a nucleus surrounded by a membrane. Several species of protozoa can be transmitted through water and cause disease in humans, including Giardia, Cryptosporidium, Cyclospora, Entamoeba and Isospora. Wikipedia

Craniocerebral Trauma

Brain-computer interfaces • Traumatic Brain InjuryBrain regions • Clinical neuropsychologyCognitive neuroscience • Human brainNeuroanatomy • NeurophysiologyPhrenology • Common misconceptions Wikipedia

Neoplasms, Squamous Cell

Neoplasms composed of squamous cells of the epithelium. The concept does not refer to neoplasms located in tissue composed of squamous elements. Wikipedia

Muscular Diseases

Muscle (from Latin musculus, diminutive of mus mouse[1]) is contractile tissue of the body and is derived from the mesodermal layer of embryonic germ cells. Muscle cells contain contractile filaments that move past each other and change the size of the cell. They are classified as skeletal, cardiac, or smooth muscles. Their function is to produce force and cause motion. Muscles can cause either locomotion of the organism itself or movement of internal organs. Cardiac and smooth muscle contraction occurs without conscious thought and is necessary for survival. Examples are the contraction of the heart and peristalsis which pushes food through the digestive system. Voluntary contraction of the skeletal muscles is used to move the body and can be finely controlled. Examples are movements of the eye, or gross movements like the quadriceps muscle of the thigh. There are two broad types of voluntary muscle fibers: slow twitch and fast twitch. Slow twitch fibers contract for long periods of time but with little force while fast twitch fibers contract quickly and powerfully but fatigue very rapidly. Wikipedia

Renal Insufficiency

Renal failure or kidney failure is a situation in which the kidneys fail to function adequately. It is divided in acute and chronic forms; either form may be due to a large number of other medical problems. Wikipedia

Brain Neoplasms

A brain tumor is any intracranial tumor created by abnormal and uncontrolled cell division, normally either in the brain itself (neurons, glial cells (astrocytes, oligodendrocytes, ependymal cells), lymphatic tissue, blood vessels), in the cranial nerves (myelin-producing Schwann cells), in the brain envelopes (meninges), skull, pituitary and pineal gland, or spread from cancers primarily located in other organs (metastatic tumors). Primary (true) brain tumors are commonly located in the posterior cranial fossa in children and in the anterior two-thirds of the cerebral hemispheres in adults, although they can affect any part of the brain. In the United States in the year 2005, it was estimated that there were 43,800 new cases of brain tumors (Central Brain Tumor Registry of the United States, Primary Brain Tumors in the United States, Statistical Report, 2005 - 2006),[1] which accounted for 1.4 percent of all cancers, 2.4 percent of all cancer deaths,[2] and 20–25 percent of pediatric cancers.[2][3] Ultimately, it is estimated that there are 13,000 deaths/year as a result of brain tumors.[1] Wikipedia

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