Steve Austad’s paper in Journal of Comparative Pathology (PubMed), Methusaleh’s Zoo: How Nature provides us with Clues for Extending Human Health Span, promotes the idea that “exceptionally long-lived organisms have important roles to play in our future understanding of the causal mechanisms and modulation of ageing.” Austad writes that most of what is known about the aging process is derived from experiments performed on short-lived laboratory species like Drosophila melanogaster, Caenorhabditis elegans and Mus musculus. He suggests that studying long-lived species such as naked mole-rats (Heterocephalus glaber) and some bats like Myotis brandti that lives for 41 years, might offer insight into the mechanisms of the aging processes. There are many more species to discover and study. As Austad concludes: “However, with the dramatic acceleration in our genome sequencing capability, it is likely that new investigatory tools for these species of exceptional gerontological interest will be developed at an accelerating pace. The role of Methusaleh’s Zoo in ageing research is likely to blossom in the near future.”
Methusaleh’s Zoo
January 25th, 2010 · 2 Comments
Tags: Aging Review Article · Hot article · Scientific research








2 responses so far ↓
1 New blog post: Methusalehu2019s Zoo … — biotweets.org // Jan 25, 2010 at 6:34 pm
[...] blog post: Methusalehu2019s Zoo http://bit.ly/6Imj5K #biodiv [...]
2 Genebean // Feb 20, 2010 at 1:45 pm
Yes, we might want to study species that apparently do not age at all such as the pacific rockfish. There is a growing sentiment that evolution selected aging because it serves an evolutionary purpose and that therefore we are purposely programmed to age and studying the non-aging species might allow distinguishing aspects of the program.
Leave a Comment