Steve Austad’s paper in Journal of Comparative Pathology (PubMed), Methusaleh’s Zoo: How Nature provides us with Clues for Extending Human Health Span, promotes the idea that “exceptionally long-lived organisms have important roles to play in our future understanding of the causal mechanisms and modulation of ageing.” Austad writes that most of what is known about [...]

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Caleb Finch’s (University of Southern California) review: Update on Slow Aging and Negligible Senescence – A Mini-Review, recently published in the journal Gerontology, explains the concept of negligible senescence he developed about 20 years ago. Since formulating this hypothesis he has been searching for organisms that display slow aging. In this review he discusses several [...]

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In their recently published review article, Matthew Piper and Andrzej Bartke from University College London review dietary (calorie) restriction as studied in rodents, Drosophila and C. elegans and “discuss examples of diet/genotype interactions that show a more complex mechanistic view is required and that mild dietary modifications can dramatically change the interpretation of model organism [...]

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